Consider sufferers for amplified respiratory and CNS melancholy when morphine sulfate tablets are applied concomitantly with cimetidine.

Morphine is thought to be substantially excreted through the kidney, and the risk of adverse reactions to this drug could be greater in individuals with impaired renal perform.

Consider prescribing naloxone if the patient has family users (such as children) or other close contacts in danger for accidental ingestion or overdose.

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